| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Items | Standard |
| Characteristics | Pale yellow crystalline powder |
| Identification | A:IR Absorption B:HPLC |
| Melting range | 110-114ºC( does not exceed 2ºC) |
| Loss on drying | Not more than 0.5% |
| Residue on ignition | Not more than 0.1% |
| Related compounds | 4-Nitro-3-trifluoro-methylacetanilide: NMT: 0.2% |
| 4-Nitro-3-trifluoro-methylaniline: NMT: 0.15% |
|
| NMT: 0.2% |
|
| 4-Nitro-3-trifluoromethylpropionanilide: NMT: 0.3% | |
| 3-trifluoromethylisobutyranilide: NMT: 0.2% |
|
| o-Flutamide:NMT: 0.2% | |
| Unknown(relative response:1.0) : NMT: 0.05% |
|
| Total unknown:NMT: 0.1% | |
| Total impurities:NMT: 0.4% | |
| Residual solvents | Meth anol:NMT:3000ppm |
| Solubility | Freely soluble in acetonemia soluble in chloroformate other practically insoluble mineral oil. and water |
| Heavy Metals | Not more than10ppm |
| Assay | 98.0-101.0% (calculated on the dried basis) |
Flutamide is a kind of synthetic, non-steroidal antiandrogen which is mainly used for the treatment of prostate cancer. It is a kind of toluidine derivative and a nonsteroidal antiandrogen .The mechanism of its anti-cancer property is through acting as a selective antagonist of the androgen receptor (AR).
Flutamide is a nonsteroidal antiandrogen drug; antineoplastic (hormonal).
Flutamide acts as a selective antagonist of the androgen receptor (AR), competing with androgens like te.stosterone and DHT for binding to ARs in tissues like the prostate gland. By doing so, it prevents their effects and stops them from stimulating prostate cancer cells to grow. Flutamide is a prodrug to a more active form. Flutamide and its active form stay in the body for a relatively short time, which makes it necessary to take flutamide multiple times per day.
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