| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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1. Product name: vitamin D3
2. CAS: 8024-19-9
3. Specification : 100,00000 iu/g
4. Molecular Formula : C27H44O
5. Appearance : Yellow oil
6. Introduction
Vitamin D3 is a fatsoluble vitamin, is used as a precursor for calcium, phosphorus metabolic hormones,it has close relationship with sunshine, so also called the "sunshine vitamin". Vitamin D3 is fatsoluble, insoluble in water, can dissolve in fat or fat solvents, high temperature and oxidation in neutral and alkaline solution.
1. Improve the body's absorption of calcium and phosphorus, so that plasma calcium and plasma phosphorus levels reach saturation.
2. Promote growth and bone calcification, and promote healthy teeth;
3. Increase the absorption of phosphorus through the intestinal wall and increase the reabsorption of phosphorus through the renal tubules;
4. Maintain the normal level of citrate in the blood;
5. Prevent the loss of amino acids through the kidneys.
Vitamin D3 is produced by the action of sunlight or ultraviolet irradiation from the precursor, 7-dehydrocholesterol (7-DC), that is synthesized in the skin of animals and humans.
In most tissues of the body, 7-dehydrocholesterol is the immediate precursor of cholesterol. It is reduced to cholesterol by the enzyme 3β-hydroxysterol-Δ7-reductase (DHCR7) in the last step of cholesterol biosynthesis. 7-DHC accumulates in Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in the DHCR7 gene and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features. It is highly susceptible to free radical oxidation, giving rise to several oxysterols that may be involved in the pathogenesis of SLOS. 7-DHC levels are increased in brain, liver, and serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944. 7-DHC is a provitamin that is converted to vitamin D3 by ultraviolet-B (UVB) light in a human skin equivalent system and in isolated human skin samples.
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