Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder

Product Details
Customization: Available
Powder: Yes
Customized: Customized
Gold Member Since 2022

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Number of Employees
1
Year of Establishment
2022-02-18
  • Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder
  • Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder
  • Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder
  • Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder
  • Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder
  • Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder
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  • Overview
  • Product Description
  • Function
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Overview

Basic Info.

Model NO.
MEI----28450
Suitable for
Elderly, Children, Adult
State
Solid
Purity
>99%
Test Method
HPLC
Storage
Store Cool Dry Place
Market
Worldwide
Mf
C43h67n11o12s2
MW
994.189
CAS
90779-69-4
Boiling Point
1469.0±65.0 °c at 760 Mmhg
Transport Package
Aluminium Foil Bag
Specification
99%
Trademark
Meister
Origin
China
Production Capacity
2000kg/Month

Product Description

Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder
Product Description

 

Product Name Atosiban/Atosiban Impurtiy 
CAS NO. 90779-69-4
Appearance White Powder
Purity 99%
Density 1.254±0.06 g/cm3
Boiling Point  1469.0±65.0 °C
Acidity Coefficient (pKa) 12.81±0.70
Solubility H2O: ≤100 mg/mL
Chemical Structure  
Application Drug peptides, Intermediates&Fine Chemicals
Usage Competitive antagonist of the cyclic peptide oxytocin receptor in the uterus, decidua and fetal membranes.
Storage Sealed containers at cool and dry place.Protect from sunlight, moisture and pest infestation.
Atosiban was introduced  as an injectable inhibitor of preterm labor, a major cause of infant morbidity and mortality. This peptidic oxytocin analog is an antagonist of the vasopressin V1a receptor and of the oxytocin receptor which is found in dramatically increased concentration in the uterine myometrium of pregnant women near term. It competitively inhibited contractions in the pregnant guinea pig uterus induced by oxytocin and vasopressin. In a multicenter, double-blind, placebo-controlled trial, treatment with atosiban caused pregnancy prolongation for up to 7 days in women with more than 28 weeks of gestation. In a comparative clinical trial, atosiban showed a comparable tocolytic action (uterine relaxant) to ritodrine but the former was significantly better tolerated, especially with regards to maternal cardiovascular side effects. In healthy volunteers, plasma levels of atosiban decreased bi-exponentially with an initial and a terminal half-life of 21 min and 1.7h respectively.
Function

Atosiban was introduced in the UK as an injectable inhibitor of preterm labor, a major cause of infant morbidity and mortality. This peptidic oxytocin analog is an antagonist of the vasopressin V1a receptor and of the oxytocin receptor which is found in dramatically increased concentration in the uterine myometrium of pregnant women near term. It competitively inhibited contractions in the pregnant guinea pig uterus induced by oxytocin and vasopressin. In a multicenter, double-blind, placebo-controlled trial, treatment with atosiban caused pregnancy prolongation for up to 7 days in women with more than 28 weeks of gestation. In a comparative clinical trial, atosiban showed a comparable tocolytic action (uterine relaxant) to ritodrine but the former was significantly better tolerated, especially with regards to maternal cardiovascular side effects. 

Application

Atosiban is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/oxytocin receptor antagonist (VOTra). Atosiban inhibits the oxytocin-mediated release of inositol trisphosphatefrom the myometrial cell membrane. 

Atosiban is useful in improving the pregnancy outcome of in vitro fertilization-embryo transfer (IVF-ET) in patients with repeated implantation failure (RIF). The pregnancy rate improved from zero to 43.7%.

Detailed Photos

Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder

Related product

Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder

Shipping&Payment

Meister Supply 99% Medical Grade Atosiban Powder CAS 90779-69-4 Bulk Atosiban Powder

 

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