China Manufacturer Supply Baclofen Powder CAS 1134-47-0 Baclofen
Meister Supply is an enterprise committed to the development, production. sales and transportaion of chemical products. The company has a long-term cooperative relationship with Bejing Research institute of Chemical Industry and its affliated universities at home and abroad. It is a research and development enterprise of new chemicl materials for the global chemical market demand. "Continuous innovation, quality assurance" is our purpose. It integrates the research and development, industrialization and marketization of innovative chemical new materials. The company has strong technical strength, advanced equipment, strict guality management system and quality afer-sales service. Over the years, our products have been widely sold to many countries and regions, and we have established stable cooperative relations with trades and end users all over the world. Relying on a strong logistics system, we have established our own overseas warehouses in the United States, Mexico, Canada and the Netherlands. Hot local products can be shipped from overseas warehouses. Well received by local customers. It has become a powerful bridge between suppliers, traders and end users. We look forward to more
Product Description
Baclofen powder also known as β-(4-chlorophenyl)-γ-aminobutyric acid (β-(4-chlorophenyl)-GABA), used as a skeletal muscle relaxant. It is primarily used to treat spasticity. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant. It is a GABA receptor agonist, specifically of the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. It is a derivative of γ-aminobutyric acid (GABA). A beneficial property of baclofen is that tolerance to its muscle-related therapeutic benefits does not seem to occur to a significant degree - baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some people receiving intrathecal baclofen treatment.
Baclofen is a γ-aminobutyric acid derivative. It is an antispasmodics class drugs acting on the central nervous system, the brain and spinal cord as a skeletal muscle relaxants and sedatives. It take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord. Clinically it has already been used as racemic agent for treating Muscle spasticity since mid-1960s. Recent studies have also found that this product can significantly reduce the symptoms of gastroesophageal reflux and alleviating related symptoms. It can also alleviate the dystonia of children and treat the urination dysfunction caused by central spinal cord injury.
Function
1). Bone muscle spasm caused by multiple sclerosis. 2). For spasms caused by infectious, degenerative, traumatic, tumor or unexplained spinal cord disease, Such as: spastic spinal paralysis, amyotrophic lateral sclerosis, spinal cord cavitation, transverse myomyelitis, traumatic paraplegia or paralysis, spinal cord compression, spinal cord tumors and motor neuron disease. 3). Used for brain-derived muscle spasms, such as: muscle spasms caused by cerebral palsy, infantile cerebral spasm, stroke and cerebral vascular accidents, brain tumors, degenerative encephalopathy, meningitis, and craniocerebral trauma. 4). It can also be used for urinary retention caused by external sphincter.
Application
Application: Used as a skeletal muscle relaxant and tranquilizer for the spinal cord
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