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Product name:Polyethylene Glycol
1.Chemical uses
PEG is the basis of a number of laxatives. Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy.PEG is also used as an excipient in many pharmaceutical products.When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from blood.
2.Medical uses
PEG is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
PEG derivatives, such as narrow range ethoxylates, are used as surfactants.
PEG has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.
3.Biological uses
PEG is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins.
PEG is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas.
4.Commercial uses
PEG is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin).
PEG is used in a number of toothpastes as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.
Performance and use:In the pharmacy used as a dripping pill carrier, clear bowel and costive laxative.In ointment,suppositories and tablets used as disintegrant,lubricant,cementing substance and coating agent. The injection with water as menstruum was made into stable injection that used as solid dispersion camer and micro-capsule stuff or sustained release agent. In Chinese traditional medicine pills,it used as coating material.In medical soft capsule,it used as the compound of sterides.In drug analysis,it used as sensitizer dispersant and stabilizing agent,and it also used as the lubricant of surgical suture and preservatives of pathology sample.