| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Pharmaceutical grade CAS 668270-12-0 99% API Linagliptin Powder |
| Appearance | powder |
| cas | 668270-12-0 |
| Assay | 99% |
| Keywords | Linagliptin ,Linagliptin powder,API Linagliptin |
| Shelf Life | 24 months when properly stored |
| Storage | Keep in a cool, dry, dark location |
Linagliptin arose from optimization efforts of xanthine-based DPP-4 inhibitors with the initial lead identified from an HTS campaign. After optimizing the activity of the initial micromolar lead, two issues that needed to be addressed were activity for hERG and muscarinic receptor M1.
Linagliptin (TrajentaR, TradjentaTM, TrazentaTM, TrayentaTM) is an oral, highly selective inhibitor of dipeptidyl peptidase-4 and is the first agent of its class to be eliminated predominantly via a nonrenal route. Linagliptin is indicated for once daily use for the treatment of adults with type 2 diabetes mellitus.
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