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Product Name | Nitazoxanide |
Synonyms | 2-(acetolyloxy)-n-(5-nitro-2-thiazolyl)benzamide;2-(acetyloxy)-n-(5-nitro-2-thiazolyl)-benzamid;n-(5-nitro-2-thiazolyl)-salicylamidacetate(ester);n-(5-nitro-2-thiazolyl)salicylamideacetate(ester);AURORA KA-645;o-[n-(5-nitrothiazol-2-yl)carbamoyl]phenyl acetate;NITAZOXANIDE;nitazoxamide |
CAS | 55981-09-4 |
MF | C12H9N3O5S |
MW | 307.28 |
EINECS | 259-931-8 |
Product Categories | Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Heterocycles;Sulfur & Sele'nium Compounds;API;Isotope labeled API;ENDURON;Pyridines |
Nitrazoxanide is widely concerned as a highly effective, broad-spectrum anti-parasite, bacterial and fungal infection of animals and humans. It is the first and only drug approved by the U.S. Drug and Food Administration (FDA) for A drug for the treatment of Cryptosporidium.
Nitazoxanide is a broad-spectrum antiparasitic and broad-spectrum antiviral drug that is used in medicine for the treatment of various helminthic, protozoal, and viral infections. It is indicated for the treatment of infection by Cryptosporidium parvum and Giardia lamblia in immunocompetent individuals and has been repurposed for the treatment of influenza. Nitazoxanide has also been shown to have in vitro antiparasitic activity and clinical treatment efficacy for infections caused by other protozoa and helminths; emerging evidence suggests that it possesses efficacy in treating a number of viral infections as well.
Chemically, nitazoxanide is the prototype member of the thiazolides, a class of drugs which are synthetic nitrothiazolyl-salicylamide derivatives with antiparasitic and antiviral activity. Tizoxanide, an active metabolite of nitazoxanide in humans, is also an antiparasitic drug of the thiazolide class.
1. It is indicated for the treatment of infection by Cryptosporidium parvum and Giardia lamblia in immunocompetent individuals and has been repurposed for the treatment of influenza.
2. Nitazoxanide has also been shown to have in vitro antiparasitic activity and clinical treatment efficacy for infections caused by other protozoa and helminths.
3. It possesses efficacy in treating a number of viral infections as well
Nitazoxanide is used to treat diarrhea in adults and children caused by the protozoa Giardia lamblia. Nitazoxanide is also used to treat diarrhea caused by the protozoa Cryptosporidium parvum. These conditions are also sometimes referred to as travelers' diarrhea. Nitazoxanide may also be used for purposes other than those listed in this medication guide.