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According to the literature, riboflavin is mainly absorbed in the proximal small intestine after oral administration. Food can promote the absorption of riboflavin, and bile salt can accelerate the absorption of riboflavin. In the dose range of 2 ~ 25mg, the bioavailability is 50 ~ 60%. The maximum absorption of a single oral dose is 27mg, and the excess is excreted from the feces. Flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) were less absorbed. The drug enters the liver through the portal vein, enters the blood circulation, and then reaches the tissue chemicalbook. Most serum riboflavin is transported by albumin or immunoglobulin and dispersed into cells through concentration gradient. In cells, riboflavin is converted to FMN through flavin kinase, and FMN is converted to fad through fad synthase. Fad is the main form of riboflavin in tissues. Riboflavin exceeding the body's requirements is mainly excreted from the kidney, and some metabolites are also excreted from the kidney. The half-life of oral or intramuscular injection is 66 ~ 84 minutes.
Riboflavin (vitamin B2) is the essential necessity for organism in normal living as the nutriment for infant, pregnant woman,nursing mother, patient after illness and the aged.
It, involve, participates in the metabolism of carbonhydrate, protein and fat, and is the major composition of flavor protein, the transferring enzyme system of hydrogen. In clinical practice, it is applicable to perleche, glossitis, ophthalmitis,
conjunctivitis, seborrhea, scrotum inflammations with proper effect, in food and feed industry, it is widely used as food and feed additive and have the Kosher Certified.
1. Riboflavin help to improve the quality of life
2. Riboflavin treatment of Migraine
3. Riboflavin promote the development and cell regeneration
4. Riboflavin to the skin, nails, hair, the normal growth
5. Riboflavin to help eliminate the mouth, lips, tongue inflammation
6. Riboflavin to enhance visual acuity, reducing eye fatigu