| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Heparin sodium salt, used as an anticoagulant, is a mucopolysaccharide substance, is the sodium salt form of glucosamine sulfate extracted from the intestinal mucosa of pigs, cattle, and sheep. It is secreted by mast cells to be naturally presented the blood inside the human bodies. Heparin can prevent platelet aggregation and destruction, inhibit the conversion from fibrinogen to fibrin monomers, inhibit the formation of thromboplastin and fight against the pre-formed thromboplastin, and also prevent the conversion of prothrombin to thrombin and counteract the antithrombin.
Heparin sodium salt can delay or prevent blood coagulation in vitro and in vivo. Its mechanism of action is very complicated which involves many processes of coagulation process. Its role is to: 1. inhibit the formation and function of thromboplastin, thus preventing the conversion of prothrombin into thrombin; 2. Inhibit the thrombin and other coagulation factors at relative high concentrations, preventing the conversion of fibrinogen to fibrous proteins; 3. prevent platelet aggregation and destruction. In addition, the anticoagulant effect of Heparin sodium salt is still related to the negatively charged sulfate inside its molecule. Positively charged alkaline substance such as protamine or toluidine blue can all neutralize its negative charge, thus inhibiting its anticoagulant effect. Because heparin can be activated in vivo and release lipoprotein lipase, hydrolyzing the triglycerides and low-density lipoprotein in chylomicrons, so it also has a lipid-lowering effect.
1.The treatment of various diseases concurrent disseminated intravascular coagulation early.
2.Prevention of arterial and venous thrombosis and pulmonary embolism.
3.Treatment of arterial and venous thrombosis and pulmonary embolism, ischemic stroke, unstable angina (to alleviate the symptoms, prevention of myocardial infarction), acute myocardial infarction (prevention of early reinfarction and infarct extension, reduce mortality).
4.The artificial lung, peritoneal dialysis or hemodialysis as anticoagulants.
5.thrombolytic therapy as maintenance therapy.
6.used for the prevention of blood coagulation and blood bank transfusion of blood and other body save anticoagulants.
1.The treatment of various diseases concurrent disseminated intravascular coagulation early.
2.Prevention of arterial and venous thrombosis and pulmonary embolism.
3.Treatment of arterial and venous thrombosis and pulmonary embolism, ischemic stroke, unstable angina (to alleviate the symptoms, prevention of myocardial infarction), acute myocardial infarction (prevention of early reinfarction and infarct extension, reduce mortality).
4.The artificial lung, peritoneal dialysis or hemodialysis as anticoagulants.
5.thrombolytic therapy as maintenance therapy.
6.used for the prevention of blood coagulation and blood bank transfusion of blood and other body save anticoagulants.
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