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High Purity Lithocholic Acid CAS 434-13-9 Lithocholic Acid Powder
Lithocholic acid is a secondary bile acid, also known as cholic acid, 3A-hydroxycholic acid, lithocholic acid, 3A-alkanoic acid, lithocholic acid, 3-hydroxycholic acid, lithocholic acid Higher vertebrate bile.
Its molecular structure contains both hydrophilic and hydrophobic groups, so the stereo configuration of bile acids has both hydrophilic and hydrophobic properties, so bile acids have strong interfacial activity.
After reviewing the literature, it was found that lithocholic acid has more pharmacological activities, such as: inhibiting tumor growth, selectively killing breast cancer cells, and selectively inhibiting mammalian DNA polymerase activity.
Lithocholic acid (LCA) is a combined cholic acid synthesized by cholic acid and lithocholic acid in the liver. It is one of the main cholic acid components, and its content changes have important value in the diagnosis and treatment of liver diseases.
Uses : A cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones.
Uses : LD50(mouse) 3900 mg/kg po
Uses : Cholagogue;Anticholelithogenic