Customization: | Available |
---|---|
Powder: | Yes |
Customized: | Customized |
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Product Name
|
Nesiritide acetate 114471-18-0 Trade |
Appearance
|
white powder |
Assay
|
99%min, 98.0% --101.0% |
Test
|
HPLC
|
Certificate
|
ISO 9001
|
CAS
|
114471-18-0 |
MF | C143H244N50O42S4 |
Storage Temperature |
Cool Dry Place
|
Nesiritide of synthetic recombinant human B -type natriuretic peptide (recombined human B-type natriuretic peptide, rhBNP), and ventricular natural natriuretic peptide secretion sodium has the same 32 amino acid sequence . Nesiritide with guanylyl vascular smooth muscle and endothelial cells cyclase receptors, increase intracellular cGMP content , cGMP as a second messenger to make arteriovenous expansion.
Studies have shown that nesiritide make endothelin or α- adrenergic receptor agonist treatment of isolated human artery and vein dilation . In the human body, nesiritide dose- dependent reduction in heart failure patients with pulmonary capillary wedge wedge pressure (pulmonary capillarywedge pressure, PCWP) and arterial pressure.
Studies have shown that nesiritide make endothelin or α- adrenergic receptor agonist treatment of isolated human artery and vein dilation . In the human body, nesiritide dose- dependent reduction in heart failure patients with pulmonary capillary wedge wedge pressure (pulmonary capillarywedge pressure, PCWP) and arterial pressure.